Pharmacokinetics and Indications:Drostanolone Propionate is a dihydrotestosterone (DHT) derived anabolic steroid. Specifically, Masteron is the DHT hormone that has been structurally altered by the addition of a methyl group at the carbon 2 position, This protects the hormone from the metabolic breakdown by the 3-hydroxysteroid dehydrogenase enzyme, which is found in the skeletal muscle. It also greatly increases the hormone’s anabolic nature. This simple structural change is all it takes to create Drostanolone, and from here the small/short Propionate ester is attached in order to control the hormone’s release time. Drostanolone Enanthate can also be found through some underground labs, which does not have to be injected as frequently, but it is somewhat rare compared to the Propionate version. The majority of all Masteron on the market will be Drostanolone Propionate.
On a functional basis, MASTAGED is well-known for being one of the only anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This is why it has been effective in the treatment of breast cancer. In fact, the combination of MASTAGED and Nolvadex (Tamoxifen Citrate) has been shown to be far more effective than chemotherapy in the treatment of inoperable breast cancer in postmenopausal women. This also makes it a popular steroid among bodybuilders as it could actually prohibit the need for an anti-estrogen when used in the right cycle. This will also prove advantageous during the cutting phase due to the hardening effects it can provide.
MASTAGED carries relatively low anabolic and androgenic ratings; however, these ratings are somewhat misleading. It’s important to remember DHT, the basis of MASTAGED , is five times more androgenic than testosterone with a much stronger binding affinity to the androgen receptor. This again promotes a harder look and can also enhance fat loss. Most all anabolic steroids are well-noted for enhancing the metabolic rate, but strong androgens have a tendency to directly promote lipolysis.
As an anabolic, MASTAGED isn’t well-known for promoting gains in lean muscle mass. It has never been used for muscle wasting in a therapeutic sense and will almost always be found in cutting plans among performance athletes. It can, however, promote significant boosts in strength, which could prove beneficial to an athlete who may not necessarily be looking for raw mass.
Effects of MASTAGED :
Without question, the effects of MASTAGED will be displayed in the most efficient way during a cutting cycle. However, for the effects to be truly appreciated the individual will need to be extremely lean. This is why the hormone will most commonly be found at the end of bodybuilding contest prep cycles as the individual should already be fairly lean at this stage. The added Masteron will help him lose that last bit of fat that often hangs on for dear life at the end of a cycle. It will also ensure his physique appears as hard as can be. Of course, the anti-estrogenic effect will simply enhance this overall look. For those that are not competitive bodybuilder lean, it is possible that the effects of Masteron may not be all that noticeable. The individual who is under 10% body fat should be able to notice some results and produce a harder, dryer look, but much over 10% and the effects may not be all that pronounced.
As a potent androgen, MASTAGED can benefit the athlete looking for a boost in strength. This can be a very beneficial steroid for an athlete who is following a calorie restricted diet in an effort to maintain a specific bodyweight necessary for his pursuit. The individual could easily enjoy moderate increases in strength and a slight improvement in recovery and muscular endurance without unwanted body weight gain.
As a bulking agent, the effects of MASTAGED will prove to be rather week. It is possible the hormone could provide gains in mass similar to Primoged, which won’t be that strong either, if the total dose was high enough. However, the relative gain in size will be very moderate with many anabolic steroids being far more suited for this period of steroidal supplementation. There are those who may wish to include MASTAGED in a bulking plan for its anti-estrogenic and fat loss effects. The latter would ensure they kept their body fat gain minimized during off-season bulking phases, but this isn’t reason enough to use it in this phase. Body fat should be controllable without it. As for the anti-estrogenic effects, off-season cycles are normally comprised of large amounts of aromatase activity due to high doses of testosterone. Progesterone activity is also commonly high with the addition of Nandrolone compounds and possible Trenbolone. Consider additional Anadrol or Dianabol and this estrogenic activity can become very pronounced. Unfortunately, while possessing anti-estrogenic effects, Masteron will not be strong enough to combat this level of estrogenic activity.
Possible Side effects:In many ways, MASTAGED is a fairly side effect friendly anabolic steroid. Side effects of MASTAGED use most certainly exist, but most men will find this steroid highly tolerable. As for females, virilization symptoms can be strong with this steroid, but we will also find they can be managed with the right plan. In order to understand the side effects of MASTAGED , we have broken them down into their separate categories along with all you need to know.
MASTAGED does not aromatize and it does not carry any progestin nature making estrogenic side effects impossible with this steroid. This means gynecomastia and water retention will not be concerns. It also means high blood pressure that is sometimes caused by excess water retention will not be a concern. An anti-estrogen is not needed due to this steroid’s use; as discussed it can have anti-estrogenic effects itself. However, depending on the specific cycle/stack that’s implemented, an anti-estrogen may be needed.
The side effects of MASTAGED can include those of an androgenic nature. Androgenic side effects can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Thankfully this hormone carries a moderate level of total androgenic activity despite being a direct derivative of the potent androgen DHT. However, individual sensitivity will play a strong role, this steroid is well-known for greatly enhancing male pattern baldness in sensitive men far more than many anabolic steroids.
An important note; the Drostanolone hormone is not metabolized by the 5-alpha reductase enzyme. This is the enzyme responsible for reducing testosterone to dihydrotestosterone. In the case of MASTAGED , it’s already DHT; there is no reduction. As there is no reduction, there is no metabolism and nothing to inhibit. This means the androgenic nature of MASTAGED will not be strongly affected by a 5-alpha reductase inhibitor such as Finasteride.
Due to its androgenic nature, MASTAGED can produce virilization symptoms in women. Virilization symptoms can include body hair growth, a deepening of the vocal chords and clitoral enlargement. Virilization symptoms have been well-noted in breast cancer treatment plans, but this is normally due to the necessary high doses used to treat such a condition. In a performance capacity, it should be possible to use this steroid without related symptoms with a low dose. However, while individual response will dictate quite a bit, this will not be a primary recommended steroid for female athletes. If it is used and related symptoms begin to show, discontinue use immediately and they will fade away. If the symptoms are ignored, it is very possible they may set in and become irreversible.
MASTAGED can have a significant effect on cholesterol. This can result in an increase in LDL cholesterol, as well as a decrease in HDL cholesterol with the strongest emphasis on the latter. The total affect on cholesterol will not be as strong as often found in many oral steroids, specifically C17-alpha alkylated steroids. However, the total affect on cholesterol management will be stronger than compared to Nandrolone compounds or the testosterone hormone. It is also possible that Masteron could have a slight negative impact on blood pressure, but this will be a non-issue for most.
Due to the cholesterol effects of Drostanolone, cholesterol management becomes very important with this steroid. Far more important than with basic testosterone cycles or stacks including a basic 19-nor. If you already suffer from high cholesterol you should not use this anabolic steroid. If you are healthy enough for use, maintaining a cholesterol friendly lifestyle is very important. Not only does this mean a healthy diet, but it should be one that includes plenty of omega fatty acids, is limited in saturated fats as well as simple sugars. Plenty of cardiovascular activity is also advised.
MASTAGED will significantly suppress natural testosterone production making exogenous testosterone therapy important when using this steroid. Failure to include exogenous testosterone will lead most men to a low testosterone condition, which not only comes with numerous possible symptoms but is also extremely unhealthy.
As most will use MASTAGED in a cutting cycle, it’s very common not to want to use a lot of testosterone due to the high levels of estrogenic activity it can provide. If this is the case, you will find a low dose of 100-200mg per week of testosterone to be enough to combat suppression and give you the needed testosterone.
Once MASTAGED is discontinued and all exogenous steroidal hormones have cleared your system, natural testosterone production will begin again. Prior levels will not return to normal over night, this will take several months. Due to the slow recovery, Post Cycle Therapy (PCT) plans are often recommended. This will speed up the recovery greatly; however, it won’t bring your levels back to their peak, this will still take time. A PCT plan will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise and significantly cut down on the total recovery time. This natural recovery does assume no prior low testosterone condition existed. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) through improper supplementation practices.
MASTAGED is not a hepatotoxic anabolic androgenic steroid and will present no stress or damage to the liver.
The standard MASTAGED dose for adult men will normally fall in the 300-400mg per week range. Normally, this will mean an injection of 100mg every other day for a total of 6-8 weeks. This does not mean 6-8 weeks represents the total cycle, but this is a common time frame for the MASTAGED portion of a stack. Some may alternatively choose to split their dose up into a daily injection schedule, but every other day should suffice. If a Drostanolone Enanthate version is found, 1-2 injections per week will work, but such a version is somewhat rare.
For female breast cancer treatment, standard dosing calls for 100mg three times per weeks for 8-12 weeks. This will commonly lead to virilization symptoms that could be hard to reverse. However, no one can deny it’s still better than cancer. For the female athlete, 50mg per week should be more than enough for a total of 4-6 weeks. Some women may find doses closer to 100mg per week to be justified if they tolerate the hormone well. Doses of this range should be controllable for most women, but individual sensitivity must be kept in mind. Doses that go above the 100mg per week mark or beyond 4-6 weeks of use will more than likely produce virilization symptoms at some level.